The overlap between fear and anxiety brain circuits

Fear and anxiety reflect overlapping brain circuits, according to research recently published in JNeurosci. The findings highlight a need to reevaluate the existing models guiding anxiety research. While “fear” and “anxiety” are often used interchangeably, prevailing scientific theory suggests that they are distinct, with different triggers and separate brain circuits. Fear—a fleeting reaction to certain […]

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Researchers uncover early results about an existing tuberculosis vaccine

While scientists race to develop and test a vaccine effective against SARS-CoV-2, the virus that causes COVID-19, recent studies have indicated that countries with widespread BCG vaccination appear to be weathering the pandemic better than their counterparts. This has led many researchers to suspect that BCG vaccine, which immunizes against tuberculosis, might offer protection against […]

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Researchers discover potential cause of immunotherapy-related neurotoxicity

New research has uncovered the previously unknown presence of CD19—a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma—in brain cells that protect the blood brain barrier (BBB). This discovery may potentially be the cause for neurotoxicity in patients undergoing CD19 directed CAR T cell […]

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Early birds vs night owls: For diabetics, an early bedtime is best

Conducted by the University of Leicester and the University of South Australia, the study assessed the bedtime preferences (sleep chronotypes) of people with type 2 diabetes, identifying a connection between bedtimes and healthy, active lifestyles. It found that night owls (people who went to late and got up late, or ‘evening chronotypes’) have an excessively […]

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Giant spider provides promise of pain relief for irritable bowel syndrome

Molecules from the venom of one of the world’s largest spiders could help University of Queensland-led researchers tailor pain blockers for people with irritable bowel syndrome (IBS). Researchers screened 28 spiders, with the venom of the Venezuelan Pinkfoot Goliath tarantula—which has a leg-span of up to 30 centimeters—showing the most promise. The team led by […]

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